TRIS HCl (tris(hydroxymethyl)aminomethane hydrochloride), Biotech Reagent, J.T.Baker®

Supplier: Avantor
Warning

Synonyms: Tris(hydroxymethyl)methylamine hydrochloride, 2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride, Trizma® hydrochloride, Trizma(R) hydrochloride, Tris(hydroxymethyl)aminomethane hydrochloride, TRIS HCl, Tromethane hydrochloride, Tris-HCl, Tris(hydroxymethyl)methylammonium chloride, Trometamol hydrochloride, THAM HCl

Management of Change (MOC) category = R

4107-09EA 1357800.18 INR
4107-09 4107-07 4107-05 4107-F7 4107-QM 4107-F9
TRIS HCl (tris(hydroxymethyl)aminomethane hydrochloride), Biotech Reagent, J.T.Baker®
TRIS HCl (Tris-(hydroxymethyl) aminomethane hydrochloride)
Formula: NH₂C(CH₂OH)₃·HCl
MW: 157,6 g/mol
MDL Number: MFCD00012590
CAS Number: 1185-53-1

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Specification Test Results

GMP Manufactured Product
CAUTION: For Manufacturing, processing or repackaging
Assay (NH₂C(CH₂OH)₃·HCl) ≥99.0 %
Appearance (colorless crystals to white crystalline powder) Passes Test
Absorbance of a 1M Solution - 260 nm ≤ 0.06
Absorbance of a 1M Solution - 280 nm ≤ 0.06
Absorbance of a 1M Solution - 400 nm ≤ 0.01
Identification (by IR) Passes Test
Loss on Drying at 105 °C ≤ 0.5 %
Water (H₂O)(by Karl Fischer titrn) ≤ 0.5 %
Endotoxin Concentration (EU/g) ≤ 2.5
Melting Point 147 - 153 °C
pH of 0.5M Solution at 25 °C 3.5 - 5.0
Enzyme Activity - DNase Activity Passes Test
Enzyme Activity - RNase Activity Passes Test
Enzyme Activity - Protease Activity Passes Test
Trace Impurities - Sodium (Na) ≤ 50.000 ppm
Trace Impurities - Aluminum (Al) ≤ 5.000 ppm
Trace Impurities - Barium (Ba) ≤ 5 ppm
Trace Impurities - Bismuth (Bi) ≤ 5 ppm
Trace Impurities - Cadmium (Cd) ≤ 5.000 ppm
Trace Impurities - Calcium (Ca) ≤ 10.0 ppm
Trace Impurities - Cobalt (Co) ≤ 5.000 ppm
Trace Impurities - Chromium (CR) ≤ 5 ppm
Trace Impurities - Potassium (K) ≤ 50 ppm
Trace Impurities - Lithium (Li) ≤ 5 ppm
Trace Impurities - Manganese (Mn) ≤ 5 ppm
Trace Impurities - Molybdenum (Mo) ≤ 5 ppm
Trace Impurities - Nickel (Ni) ≤ 5.000 ppm
Trace Impurities - Arsenic (As) ≤ 1 ppm
Trace Impurities - Copper (Cu) ≤ 5 ppm
Trace Impurities - Iron (Fe) ≤ 5 ppm
Trace Impurities - Lead (Pb) ≤ 1 ppm
Trace Impurities - Magnesium (Mg) ≤ 5 ppm
No Class 1,2,3 or other solvents are used or produced in the
manufacturing or purification of the product.
Filtered through a 0.2 micron filter.

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