Tris(hydroxymethyl)aminomethane (TRIS, Trometamol) 99.0-101.0% USP, Multi-Compendial, J.T.Baker®
Supplier: Avantor
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Warning
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Synonyms:
2-Amino-2-(hydroxymethyl)propane-1,3-diol(tris), Tromethamine, Tris(hydroxymethyl)methylamine, 2-Amino-2-(hydroxymethyl)propane-1,3-diol, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, Trizma(R) base, TRIS base, THAM
4102-01EA
15687.52
INR
4102-01
4102-05
4102-07
4102-09
4102-F9
4102-F7
4102-F8
4102-06
4102-K3
4102-SD
4102-QM
4102-71
4102-77
4102-0F
Tris(hydroxymethyl)aminomethane (TRIS, Trometamol) 99.0-101.0% USP, Multi-Compendial, J.T.Baker®
Tris(hydroxymethyl)aminomethane (TRIS, Trometamol)
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Formula:
NH₂C(CH₂OH)₃ MW: 121,14 g/mol Boiling Pt: 357 °C (1013 hPa) Melting Pt: 169…172 °C Density: 1,328 g/cm³ (20 °C) Storage Temperature: Ambient |
MDL Number:
MFCD00004679 CAS Number: 77-86-1 EINECS: 201-064-4 Merck Index: 13,09842 |
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Specification Test Results
| Meets JPC (1997) Chemical Specifications | 99.0 - 101.0% |
| Meets B.P. Chemical Specifications | Passes Test |
| Meets E.P. Chemical Specifications | Passes Test |
| Meets U.S.P Requirements | Passes Test |
| GMP Manufactured Product | 10.0 - 11.5 |
| CAUTION: For Manufacturing, processing or repackaging | ≤1.0% |
| Bulk Pharmaceutical Chemical | ≤0.1% |
| USP - Assay (C₄H₁₁NO₃) | 99.0 - 101.0 % |
| USP - Identification A | Passes Test |
| USP - Identification B | Passes Test |
| USP - Identification C | Passes Test |
| USP - pH (1 in 20) | 10.0 - 11.5 |
| USP - Loss on Drying | ≤1.0 % |
| USP - Residue on Ignition | ≤0.1 % |
| USP - Melting Range(Lower) | 168 - 172 °C |
| USP - Melting Range(Upper) | 168 - 172 °C |
| EP/BP - Assay (C₄H₁₁NO₃) (dried basis) | 99.0 - 100.5 % |
| EP/BP - Identification B (melting point) | 168 - 174 °C |
| EP/BP - Identification C | Passes Test |
| EP/BP - Appearance of Solution | Passes Test |
| EP/BP - pH | 10.0 - 11.5 |
| EP/BP - Related Substances | ≤1.0 % |
| EP/BP - Chloride (Cl) | ≤100 ppm |
| EP/BP - Iron (Fe) | ≤10 ppm |
| EP/BP - Loss on Drying at 105°C | ≤0.5 % |
| EP/BP - Ash (sulfated) | ≤0.1 % |
| JPC 1997 - Assay (C₄H₁₁NO₃) (dried basis) | ≥99.0 % |
| JPC 1997 - Identification A | Passes Test |
| JPC 1997 - Identification B | Passes Test |
| JPC 1997 - pH | 10.3 - 10.7 |
| JPC 1997 - Melting Point | 168 - 172 °C |
| JP - Clarity and Color of Solution | Passes Test |
| JPC 1997 - Heavy Metals (as Pb) | ≤8 ppm |
| JPC 1997 - Arsenic (As) | ≤1.6 ppm |
| JPC 1997 - Loss on Drying | ≤0.5 % |
| JPC 1997 - Residue on Ignition | ≤0.10 % |
| Assay (C₄H₁₁NO₃) (dried basis) | ≥99.9 % |
| Absorbance of a 1M Solution - 260 nm | ≤0.06 |
| Absorbance of a 1M Solution - 280 nm | ≤0.06 |
| Absorbance of a 1M Solution - 400 nm | ≤0.01 |
| Endotoxin Concentration (EU/g) | ≤2.5 |
| Iron (Fe) | ≤1 ppm |
| Lead (Pb) | ≤1 ppm |
| Ultrapure Bioreagent Specifications | |
| No Class 1,2,3 or other solvents are used or produced in the | |
| manufacturing or purification of the product. | |
| Manufactured exclusively for Avantor Performance Materials, LLC., by BioSpectra, Inc., Stroudsburg, PA | |
| Elemental Impurities (USP 232, EP 5.20) - Information on elemental | |
| impurities for this product is available on the associated Product | |
| Regulatory Data Sheet and elemental impurity profile report. |
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