L(+)-Histidine monohydrochloride monohydrate, Multi-Compendial, J.T.Baker®

Supplier: Avantor

Synonyms: L-Histidine monohydrochloride monohydrate, (2S)-(+)-Histidine monohydrochloride monohydrate, L-Histidine hydrochloride monohydrate, (S)-(+)-Histidine monohydrochloride monohydrate, His HCl monohydrate, H-His-OH.HCl.H2O, H-His-OH·HCl·H₂O, L-3-Imidazol-4-ylalanine monohydrochloride monohydrate, L-Histidine hydrochloride hydrate

2081-06
2081-06EA 37423.32 INR
2081-06 2081-07
L(+)-Histidine monohydrochloride monohydrate, Multi-Compendial, J.T.Baker®
L(+)-Histidine monohydrochloride monohydrate
Formula: C₆H₉N₃O₂·HCl·H₂O
MW: 209,63 g/mol
Melting Pt: 259 °C
Density: 1,485 g/cm³ (20 °C)
Storage Temperature: Ambient
MDL Number: MFCD00151027
CAS Number: 5934-29-2
EINECS: 211-438-9
Merck Index: 13,04741
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Specification Test Results

Meets B.P. Chemical Specifications
Meets E.P. Chemical Specifications
GMP Manufactured Product
Meets J.P. Chemical Specifications
Store in airtight container.
CAUTION: For Manufacturing, processing or repackaging
Bulk Pharmaceutical Chemical
EP/BP - Assay (C₆H₉N₃O₂·HCl) (dried basis) 98.5 - 101.0 %
EP/BP - Identification A Passes Test
EP/BP - Identification B Passes Test
EP/BP - Identification C Passes Test
EP/BP - Identification F Passes Test
EP/BP - Appearance of Solution Passes Test
EP/BP - pH 3.0 - 5.0
EP/BP - Specific Rotation [Å]²º^D (+) 9.2 - 10.6 Degree
EP/BP-Ninhydrin-Positive Substances-Each ≤0.2 %
EP/BP-Ninhydrin-Positive Substances-Total Impurities ≤0.5 %
EP/BP - Sulfate (SO₄) ≤300 ppm
EP/BP - Ammonium (NH₄) ≤0.02 %
EP/BP - Iron (Fe) ≤10 ppm
EP/BP - Loss on Drying at 150°C 7.0 - 10.0 %
EP/BP - Ash (sulfated) ≤0.1 %
JP - Identification Passes Test
JP - Optical Rotation (+) 9.2 - 10.6
JP - pH 3.5 - 4.5
JP - Clarity and Color of Solution Passes Test
JP - Sulfate (SO₄) ≤0.028 %
JP - Ammonium (NH₄) ≤0.02 %
JP - Heavy Metals (as Pb) ≤10 ppm
JP - Iron (Fe) ≤10 ppm
JP - Related Substances Passes Test
JP - Water 7.2 - 10.0 %
JP - Residue on Ignition ≤ 0.10 %
JP - Assay (anhydrous basis) 99.0 - 101.0 %
Endotoxin Concentration, IU/mg ,For Information Only
No Class 1,2,3 or other solvents are used or produced in the
manufacturing or purification of the product.
No Class 1,2,3 or other solvents are used or produced in the manufacturing or purification of the product. ≤ 10 ppm
Elemental Impurities (USP 232, EP 5.20) - Information on elemental ≤ 10 ppm
impurities for this product is available on the associated Product Passes Test
Regulatory Data Sheet and elemental impurity profile report. 7.2 - 10.0 %
Elemental Impurities (USP ()232, EP 5.20) - Information on
elemental impurities for this product is available on the associated
Product Regulatory Data Sheet and elemental impurity profile report.

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