You Searched For: Bioreactors

Case Study: Masterflex® Microflex® Pump Head Used for Applikon® miniBio Bioreactor This mini 500-mL bioreactor is currently being used for COVID-19 vaccine research Applikon Biotechnology is a global leader in developing and supplying advanced bio...

Fermentation media & supplements Culture media formulation development is not mutually exclusive of the methods for clone selection or the processes used (bioreactor and cells) to achieve the desired cell density and productivity. Our broad offeri...

PEIpro Poster Reproducibility & Scalability Excellent lot-to-lot protein yield reproducibility using PEIpro®. Suspension HEK-293 cells were seeded at 1×106 cells/mL in serum-free medium and transfected with PEIpro® following the standard protocol....

1.0 0.9 0.8 0.7 0.6 0.5 rM A b (g /L ) 0.4 0.3 0.2 0.1 0 10 9 8 7 6 5 C el l d en si ty (c el ls /m L) 4 3 2 1 0 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Time (d) Feed Application note 29188433 AA GE Healthcare Production of recombinant monoclonal antib...

CleanPack - the Custom Cleanroom Packaging and Irradiation Service For example products that are not originally cleanroom compliant can be cleaned and packaged for use in a cleanroom. We can also customise or repack existing cleanroom products to ...

Cell culture Both autologous and allogeneic cells are obtained from donors utilizing methods including but not limited to apheresis aspirates and surgical biopsies. The donor cells of interest are processed to remove undesirable contaminants and p...

Bioprocessing Centrifuges Featured Solutions Fast and efficient separation of cell cultures from bioreactors or other sources at high g-forces while simplifying productivity safety and reliability: Versatile high-throughput sample processing 6 x 1...

Upstream processing for cell therapy Compared to production volumes associated with other biologics (e.g. mAbs: 2000L to 10000L) cell therapy production volumes are more commonly between 1L to 10L. Even the quality parameters are different. Instea...

Masterflex®, part of Avantor® Masterflex® Dedicated to the success of your entire fluid path from research to production since 1955 Masterflex® L/S® Digital Pump Systems Operation is easier than ever thanks to a maintenance-free, high-accuracy mot...

Avantor OmniTop Sample Tubes® adjustable volume sampling system (AVSS) Enhance the effectiveness of your sampling process with the Avantor OmniTop Sample Tubes® adjustable volume sampling system (AVSS). Designed to precisely collect small volume s...

Masterflex case studies Case Study: Masterflex® Microflex® Pump Head Used for Applikon® miniBio Bioreactor Applikon needed a very small pump head that was easy to use accurate and provided reproducible results. They reached out to the Masterflex® ...

Upstream processing for mAbs Developing and manufacturing mAbs has moved away from a dependency on raw materials of animal origin. Our biochemical components and supplements are animal component-free to meet the needs of these applications. Produc...

Présentation PowerPoint Advanced CHO Cell Expression System for Increased Transient Protein Production 0 20 40 60 80 100 0 2 4 6 8 10 12 0 24 48 72 96 120 V ia b ili ty ( % ) V ia b le C el l D en si ty ( x1 0 6 ce lls /m L) Time (h) Viable Cell D...

Upstream processing for microbial-based recombinant proteins Using microbial fermentation for the development and manufacture of recombinant proteins keeps on showing advantages e.g for the expression of proteins that do not require post-translati...

Downstream purification for mAbs Major processes including affinity ion exchange HIC and size exclusion require chromatography resins and process buffers. These products help ensure that the quality of the target mAb is maintained through each ste...

Shear-Sensitive Pumping with Peristaltic Pumps Factors Impacting Shear Sensitivity Peristaltic pumps have become the gold standard for shear-sensitive pumping applications where damage to cells or agitation of a suspension or colloidal mixture may...